1jks Summary

pdbe.org/1jks
spacer

1.5A X-RAY STRUCTURE OF APO FORM OF A CATALYTIC DOMAIN OF DEATH-ASSOCIATED PROTEIN KINASE

The structure was published by Tereshko, V., Teplova, M., Brunzelle, J., Watterson, D.M., and Egli, M., in 2001 in a paper entitled "Crystal structures of the catalytic domain of human protein kinase associated with apoptosis and tumor suppression." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.5 Å and deposited in 2001.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of DEATH-ASSOCIATED PROTEIN KINASE. This molecule has the UniProt identifier P53355 (DAPK1_HUMAN)search. The sample contained 294 residues which is < 90% of the natural sequence. Out of 294 residues 279 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A DEATH-ASSOCIATED PROTEIN KINASE P53355 (2-285) (DAPK1_HUMAN)search Homo sapienssearch < 90% 294 95%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P53355 (2 - 285) DEATH-ASSOCIATED PROTEIN KINASE Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Protein kinases, catalytic subunitsearch Phosphorylase Kinase; domain 1search, Transferase(Phosphotransferase) domain 1search Protein kinase domainsearch

Chain ID Biological process (GO) Molecular function (GO)
A (P53355) protein phosphorylationsearch ATP bindingsearch transferase activity, transferring phosphorus-containing groupssearch protein kinase activitysearch protein serine/threonine kinase activitysearch

Chain InterPro annotation
A Protein kinase domainsearch Serine/threonine/dual specificity protein kinase, catalytic domainsearch Serine/threonine-protein kinase, active sitesearch Protein kinase-like domainsearch Protein kinase, ATP binding sitesearch Myosin light chain kinase-relatedsearch Death-associated protein kinase 1search