1jk1 Summary

pdbe.org/1jk1
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Zif268 D20A Mutant Bound to WT DNA Site

The structure was published by Miller, J.C. and Pabo, C.O., in 2001 in a paper entitled "Rearrangement of side-chains in a Zif268 mutant highlights the complexities of zinc finger-DNA recognition." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.9 Å and deposited in 2001.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 3 biomacromolecules, namely 5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*CP*GP*G)-3', 5'-D(*TP*CP*CP*GP*CP*CP*CP*AP*CP*GP*C)-3', and ZIF268.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A ZIF268 P08046 (333-421) (EGR1_MOUSE)search Mus musculussearch < 90% 90 94%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P08046 (333 - 421) ZIF268 Mus musculus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Classic zinc finger, C2H2search Classic Zinc Fingersearch Zinc-finger double domainsearch

Chain ID Molecular function (GO)
A (P08046) nucleic acid bindingsearch metal ion bindingsearch

Chain InterPro annotation
A Zinc finger, C2H2search Zinc finger C2H2-type/integrase DNA-binding domainsearch Zinc finger, C2H2-likesearch