1jgg Summary

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Even-skipped Homeodomain Complexed to AT-rich DNA

The structure was published by Hirsch, J.A. and Aggarwal, A.K., in 1995 in a paper entitled "Structure of the even-skipped homeodomain complexed to AT-rich DNA: new perspectives on homeodomain specificity." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2001.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 3 biomacromolecules, namely 5'-D(P*TP*AP*AP*TP*TP*GP*AP*AP*TP*T)-3', 5'-D(P*AP*AP*TP*TP*CP*AP*AP*TP*TP*A)-3', and Segmentation Protein Even-Skipped.

The molecule most likely forms heterotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Segmentation Protein Even-Skipped P06602 (70-129) (EVE_DROME)search Drosophila melanogastersearch < 90% 60 95%
B Segmentation Protein Even-Skipped P06602 (70-129) (EVE_DROME)search Drosophila melanogastersearch < 90% 60 95%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P06602 (70 - 129) Segmentation Protein Even-Skipped Drosophila melanogaster

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B Homeodomainsearch Homeodomain-likesearch Homeobox domainsearch

Chain ID Biological process (GO) Molecular function (GO)
A, B (P06602) regulation of transcription, DNA-templatedsearch DNA bindingsearch sequence-specific DNA bindingsearch

Chain InterPro annotation
A, B Homeobox domainsearch Homeodomain-likesearch Homeobox, conserved sitesearch Homeodomain, metazoasearch