1jfz Summary

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Crystal Structure of MN(II)-Complex of RNAse III Endonuclease Domain from Aquifex Aeolicus at 2.10 Angstrom Resolution

The structure was published by Blaszczyk, J., Tropea, J.E., Bubunenko, M., et al., Waugh, D.S., Court, D.L., and Ji, X., in 2001 in a paper entitled "Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.1 Å and deposited in 2001.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of RIBONUCLEASE III.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A RIBONUCLEASE III O67082 (1-147) (RNC_AQUAE)search Aquifex aeolicus VF5search 100% 154 96%
B RIBONUCLEASE III O67082 (1-147) (RNC_AQUAE)search Aquifex aeolicus VF5search 100% 154 96%
C RIBONUCLEASE III O67082 (1-147) (RNC_AQUAE)search Aquifex aeolicus VF5search 100% 154 96%
D RIBONUCLEASE III O67082 (1-147) (RNC_AQUAE)search Aquifex aeolicus VF5search 100% 154 96%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
O67082 (1 - 147) RIBONUCLEASE III Aquifex aeolicus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B, C, D (O67082) RNase III catalytic domain-likesearch Ribonuclease iii, N-terminal Endonuclease Domain; Chain Asearch PF00636: Ribonuclease III domainsearch

Chain ID Molecular function (GO) Biological process (GO)
A, B, C, D (O67082) ribonuclease III activitysearch RNA bindingsearch rRNA catabolic processsearch RNA processingsearch

Chain InterPro annotation
A, B, C, D Ribonuclease III domainsearch Ribonuclease IIIsearch