1jfg Summary

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TRICHODIENE SYNTHASE FROM FUSARIUM SPOROTRICHIOIDES COMPLEXED WITH DIPHOSPHATE

The structure was published by Rynkiewicz, M.J., Cane, D.E., and Christianson, D.W., in 2001 in a paper entitled "Structure of trichodiene synthase from Fusarium sporotrichioides provides mechanistic inferences on the terpene cyclization cascade." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 2001.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of TRICHODIENE SYNTHASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A TRICHODIENE SYNTHASE P13513 (1-374) (TRI5_FUSSP)search Fusarium sporotrichioidessearch 100% 374 94%
B TRICHODIENE SYNTHASE P13513 (1-374) (TRI5_FUSSP)search Fusarium sporotrichioidessearch 100% 374 94%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P13513 (1 - 374) TRICHODIENE SYNTHASE Fusarium sporotrichioides

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P13513) Trichodiene synthasesearch Farnesyl Diphosphate Synthasesearch PF06330: Trichodiene synthase (TRI5)search

Chain ID Biological process (GO) Molecular function (GO)
A, B (P13513) sesquiterpenoid biosynthetic processsearch lyase activitysearch trichodiene synthase activitysearch

Chain InterPro annotation
A, B Terpenoid synthasesearch Trichodiene synthase, ascomycetessearch Trichodiene synthasesearch