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EBI PDBe PDBeView

PDBe Entry: 1j7l view

Crystal Structure of 3',5"-Aminoglycoside Phosphotransferase Type IIIa ADP Complex
Summary
Header TRANSFERASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.2 Å, R-factor: 22.0%, Free R-factor: 27.9%, Spacegroup: P 21 21 21
Released 08/08/2001, deposition: 17/05/2001, last revision: 24/02/2009
Authors Burk, D.L.search; Hon, W.C.search; Leung, A.K.-W.search; Berghuis, A.M.search
Primary citation Structural analyses of nucleotide binding to an aminoglycoside phosphotransferase.
BIOCHEMISTRYsearch vol:40, pag:8756-8764 (2001) [PubMed ID 11467935 ]search
Keywords antibiotic resistancesearch, kinasesearch, ATP-bindingsearch, TRANSFERASEsearch
EC 2.7.1.95 ExPASy BRENDA search (A B)
Organism Enterococcus faecalis 1351search(A B)
UniProt Aminoglycoside 3'-phosphotransferase (EC 2.7.1.95) (Kanamycin kinase, type III) (Neomycin-kanamycin phosphotransferase type III) (APH(3')III) P0A3Y5search (A B)
Solvent A, B
Related entries 1j7i, 1j7u
Polymers
Id Name Type UniProt Residues Observed
A, B AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE Protein P0A3Y5 (KKA3_ENTFA)search
 264 99%
Heterogens
Id Name Ligands
A, B MAGNESIUM ION MG search
A, B ADENOSINE-5'-DIPHOSPHATE ADP search
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