› 1j5k

Solution NMR

COMPLEX OF THE KH3 DOMAIN OF HNRNP K WITH A SINGLE_STRANDED 10MER DNA OLIGONUCLEOTIDE

Released:
DOI: 10.2210/pdb1j5k/pdb
PDB entry 1j5k coloured by chain, front view.
PDB entry 1j5k coloured by chain, side view.
PDB entry 1j5k coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Molecular basis of sequence-specific single-stranded DNA recognition by KH domains: solution structure of a complex between hnRNP K KH3 and single-stranded DNA.
Braddock DT, Baber JL, Levens D, Clore GM
EMBO J 21 3476-85 (2002)
PMID: 12093748

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113989 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
Heterogeneous nuclear ribonucleoprotein K Chain: A
Molecule details ›
Chain: A
Length: 89 amino acids
Theoretical weight: 9.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61978 (Residues: 379-463; Coverage: 18%)
Gene names: HNRNPK, HNRPK
Sequence domains: KH domain
Structure domains: K Homology domain, type 1
5'-D(*AP*TP*AP*T*TP*CP*CP*CP*TP*C)-3' Chain: B
Molecule details ›
Chain: B
Length: 10 nucleotides
Theoretical weight: 2.95 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

15 review citations

RNA-binding proteins: modular design for efficient function.
Lunde et al. (2007)
14 more

5 mentions without citation

Molecular basis of sequence-specific single-stranded DNA recognition by KH domains: solution structure of a complex between hnRNP K KH3 and single-stranded DNA.
Braddock et al. (2002)
4 more