› › Structure analysis

HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE C124S MUTANT-PEPTIDE COMPLEX

X-ray diffraction
2.75Å resolution
PDB entry 1j4x coloured by chain, front view.
PDB entry 1j4x coloured by chain, side view.
PDB entry 1j4x coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Dual specificity protein phosphatase 3 and peptide
hide full assembly name
Multimeric state: hetero dimer
Accessible surface area: 9136.24 Å2
Buried surface area: 1240.89 Å2
Dissociation area: 620.45 Å2
Dissociation energy (ΔGdiss): 10.54 kcal/mol
Dissociation entropy (TΔSdiss): 8.18 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-156341

Macromolecules

Dual specificity protein phosphatase 3
Chain: A
Length: 184 amino acids
Theoretical weight: 20.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P51452 (Residues: 2-185; Coverage: 100%)
Gene names: DUSP3, VHR
Pfam: Dual specificity phosphatase, catalytic domain
InterPro:
CATH: Protein tyrosine phosphatase superfamily
SCOP: Dual specificity phosphatase-like
Dual specificity protein phosphatase 3 in PDB entry 1j4x, assembly 1, front view.
Dual specificity protein phosphatase 3 in PDB entry 1j4x, assembly 1, side view.
Dual specificity protein phosphatase 3 in PDB entry 1j4x, assembly 1, top view.
Molecule details ›

Search similar proteins

DDE(AHP)(TPO)G(PTR)VATR
Chain: D
Length: 11 amino acids
Theoretical weight: 1.41 KDa
Source organism: Homo sapiens
Expression system: Not provided
DDE(AHP)(TPO)G(PTR)VATR in PDB entry 1j4x, assembly 1, front view.
DDE(AHP)(TPO)G(PTR)VATR in PDB entry 1j4x, assembly 1, side view.
DDE(AHP)(TPO)G(PTR)VATR in PDB entry 1j4x, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links