› 1j1j

X-ray diffraction
2.2Å resolution

Crystal Structure of human Translin

Released:
DOI: 10.2210/pdb1j1j/pdb
PDB entry 1j1j coloured by chain, front view.
PDB entry 1j1j coloured by chain, side view.
PDB entry 1j1j coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of human translin at 2.2 A resolution.
Sugiura I, Sasaki C, Hasegawa T, Kohno T, Sugio S, Moriyama H, Kasai M, Matsuzaki T
Acta Crystallogr D Biol Crystallogr 60 674-9 (2004)
PMID: 15039555

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo tetramer
homo dimer (preferred)
homo octamer
Assembly name:
PDBe Complex ID:
PDB-CPX-172343 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Translin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 240 amino acids
Theoretical weight: 27.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15631 (Residues: 1-228; Coverage: 100%)
Gene name: TSN
Sequence domains: Translin family
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL24XU
Spacegroup: C2221
Unit cell:
a: 129.42Å b: 135.27Å c: 134.35Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.231 0.229 0.265
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Biological roles of translin and translin-associated factor-X: RNA metabolism comes to the fore.
Jaendling et al. (2010)
3 more

12 mentions without citation

C3PO, an endoribonuclease that promotes RNAi by facilitating RISC activation.
Liu et al. (2009)
11 more