1ird Summary

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Crystal Structure of Human Carbonmonoxy-Haemoglobin at 1.25 A Resolution

A publication describing this structure is not available. The depositing authors are Park, S.-Y.search; Tame, J.R.H.search

This crystal structure was determined using X-ray diffraction at a resolution of 1.25 Å and deposited in 2001.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Hemoglobin alpha chain and Hemoglobin beta chain.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Hemoglobin alpha chain P69905 (2-142) (HBA_HUMAN)search Homo sapienssearch 98% 141 100%
B Hemoglobin beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P69905 (2 - 142) Hemoglobin alpha chain Homo sapiens
P68871 (2 - 147) Hemoglobin beta chain Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P69905) Globinssearch Globinssearch PF00042: Globinsearch
B (P68871) Globinssearch Globinssearch PF00042: Globinsearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A (P69905) oxygen bindingsearch heme bindingsearch peroxidase activitysearch haptoglobin bindingsearch protein bindingsearch oxygen transporter activitysearch iron ion bindingsearch metal ion bindingsearch oxygen transportsearch receptor-mediated endocytosissearch oxidation-reduction processsearch transportsearch bicarbonate transportsearch positive regulation of cell deathsearch small molecule metabolic processsearch response to hydrogen peroxidesearch hydrogen peroxide catabolic processsearch protein heterooligomerizationsearch extracellular regionsearch membranesearch extracellular vesicular exosomesearch endocytic vesicle lumensearch cytosolsearch cytosolic small ribosomal subunitsearch hemoglobin complexsearch haptoglobin-hemoglobin complexsearch blood microparticlesearch
B (P68871) iron ion bindingsearch oxygen bindingsearch heme bindingsearch oxygen transporter activitysearch protein bindingsearch peroxidase activitysearch haptoglobin bindingsearch hemoglobin bindingsearch metal ion bindingsearch oxygen transportsearch response to hydrogen peroxidesearch blood coagulationsearch hydrogen peroxide catabolic processsearch positive regulation of cell deathsearch bicarbonate transportsearch regulation of blood pressuresearch oxidation-reduction processsearch renal absorptionsearch nitric oxide transportsearch receptor-mediated endocytosissearch small molecule metabolic processsearch positive regulation of nitric oxide biosynthetic processsearch regulation of blood vessel sizesearch transportsearch platelet aggregationsearch protein heterooligomerizationsearch haptoglobin-hemoglobin complexsearch hemoglobin complexsearch extracellular regionsearch cytosolsearch extracellular vesicular exosomesearch blood microparticlesearch endocytic vesicle lumensearch

Chain InterPro annotation
A Globinsearch Haemoglobin, alphasearch Haemoglobin, pisearch Globin-likesearch Globin, structural domainsearch
B Globinsearch Haemoglobin, betasearch Globin-likesearch Globin, structural domainsearch