1ird Summary

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Crystal Structure of Human Carbonmonoxy-Haemoglobin at 1.25 A Resolution

A publication describing this structure is not available. The depositing authors are Park, S.-Y.search; Tame, J.R.H.search

This crystal structure was determined using X-ray diffraction at a resolution of 1.25 Å and deposited in 2001.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Hemoglobin alpha chain and Hemoglobin beta chain.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Hemoglobin alpha chain P69905 (2-142) (HBA_HUMAN)search Homo sapienssearch 98% 141 100%
B Hemoglobin beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P69905 (2 - 142) Hemoglobin alpha chain Homo sapiens
P68871 (2 - 147) Hemoglobin beta chain Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P69905) Globinssearch Globinssearch PF00042: Globinsearch
B (P68871) Globinssearch Globinssearch PF00042: Globinsearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A (P69905) iron ion bindingsearch oxygen bindingsearch protein bindingsearch haptoglobin bindingsearch metal ion bindingsearch peroxidase activitysearch heme bindingsearch oxygen transporter activitysearch endocytic vesicle lumensearch membranesearch extracellular vesicular exosomesearch extracellular regionsearch cytosolsearch hemoglobin complexsearch cytosolic small ribosomal subunitsearch blood microparticlesearch haptoglobin-hemoglobin complexsearch bicarbonate transportsearch oxidation-reduction processsearch transportsearch response to hydrogen peroxidesearch hydrogen peroxide catabolic processsearch oxygen transportsearch positive regulation of cell deathsearch protein heterooligomerizationsearch small molecule metabolic processsearch
B (P68871) protein bindingsearch oxygen transporter activitysearch metal ion bindingsearch hemoglobin bindingsearch haptoglobin bindingsearch peroxidase activitysearch oxygen bindingsearch iron ion bindingsearch heme bindingsearch hemoglobin complexsearch extracellular vesicular exosomesearch extracellular regionsearch blood microparticlesearch cytosolsearch endocytic vesicle lumensearch haptoglobin-hemoglobin complexsearch positive regulation of cell deathsearch nitric oxide transportsearch bicarbonate transportsearch hydrogen peroxide catabolic processsearch response to hydrogen peroxidesearch small molecule metabolic processsearch oxygen transportsearch transportsearch regulation of blood pressuresearch renal absorptionsearch platelet aggregationsearch blood coagulationsearch regulation of blood vessel sizesearch oxidation-reduction processsearch protein heterooligomerizationsearch positive regulation of nitric oxide biosynthetic processsearch

Chain InterPro annotation
A Globinsearch Haemoglobin, alphasearch Haemoglobin, pisearch Globin-likesearch Globin, structural domainsearch
B Globinsearch Haemoglobin, betasearch Globin-likesearch Globin, structural domainsearch