1ird Summary

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Crystal Structure of Human Carbonmonoxy-Haemoglobin at 1.25 A Resolution

A publication describing this structure is not available. The depositing authors are Park, S.-Y.search; Tame, J.R.H.search

This crystal structure was determined using X-ray diffraction at a resolution of 1.25 Å and deposited in 2001.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Hemoglobin alpha chain and Hemoglobin beta chain.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Hemoglobin alpha chain P69905 (2-142) (HBA_HUMAN)search Homo sapienssearch 98% 141 100%
B Hemoglobin beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P69905 (2 - 142) Hemoglobin alpha chain Homo sapiens
P68871 (2 - 147) Hemoglobin beta chain Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P69905) Globinssearch Globinssearch PF00042: Globinsearch
B (P68871) Globinssearch Globinssearch PF00042: Globinsearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A (P69905) heme bindingsearch oxygen bindingsearch iron ion bindingsearch haptoglobin bindingsearch peroxidase activitysearch protein bindingsearch metal ion bindingsearch oxygen transporter activitysearch hemoglobin complexsearch membranesearch extracellular vesicular exosomesearch extracellular regionsearch cytosolsearch endocytic vesicle lumensearch cytosolic small ribosomal subunitsearch haptoglobin-hemoglobin complexsearch blood microparticlesearch oxygen transportsearch oxidation-reduction processsearch bicarbonate transportsearch positive regulation of cell deathsearch protein heterooligomerizationsearch transportsearch small molecule metabolic processsearch response to hydrogen peroxidesearch hydrogen peroxide catabolic processsearch
B (P68871) iron ion bindingsearch heme bindingsearch oxygen transporter activitysearch protein bindingsearch hemoglobin bindingsearch oxygen bindingsearch peroxidase activitysearch haptoglobin bindingsearch metal ion bindingsearch extracellular vesicular exosomesearch haptoglobin-hemoglobin complexsearch hemoglobin complexsearch extracellular regionsearch cytosolsearch blood microparticlesearch endocytic vesicle lumensearch oxygen transportsearch transportsearch response to hydrogen peroxidesearch bicarbonate transportsearch hydrogen peroxide catabolic processsearch renal absorptionsearch nitric oxide transportsearch oxidation-reduction processsearch positive regulation of cell deathsearch blood coagulationsearch regulation of blood vessel sizesearch small molecule metabolic processsearch protein heterooligomerizationsearch regulation of blood pressuresearch positive regulation of nitric oxide biosynthetic processsearch

Chain InterPro annotation
A Globinsearch Haemoglobin, alphasearch Haemoglobin, pisearch Globin-likesearch Globin, structural domainsearch
B Globinsearch Haemoglobin, betasearch Globin-likesearch Globin, structural domainsearch