1ird Summary

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Crystal Structure of Human Carbonmonoxy-Haemoglobin at 1.25 A Resolution

A publication describing this structure is not available. The depositing authors are Park, S.-Y.search; Tame, J.R.H.search

This crystal structure was determined using X-ray diffraction at a resolution of 1.25 Å and deposited in 2001.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Hemoglobin alpha chain and Hemoglobin beta chain.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Hemoglobin alpha chain P69905 (2-142) (HBA_HUMAN)search Homo sapienssearch 98% 141 100%
B Hemoglobin beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P69905 (2 - 142) Hemoglobin alpha chain Homo sapiens
P68871 (2 - 147) Hemoglobin beta chain Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P69905) Globinssearch Globinssearch PF00042: Globinsearch
B (P68871) Globinssearch Globinssearch PF00042: Globinsearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A (P69905) iron ion bindingsearch heme bindingsearch protein bindingsearch metal ion bindingsearch oxygen transporter activitysearch oxygen bindingsearch peroxidase activitysearch haptoglobin bindingsearch bicarbonate transportsearch oxygen transportsearch transportsearch positive regulation of cell deathsearch response to hydrogen peroxidesearch hydrogen peroxide catabolic processsearch small molecule metabolic processsearch protein heterooligomerizationsearch oxidation-reduction processsearch cytosolic small ribosomal subunitsearch extracellular regionsearch hemoglobin complexsearch haptoglobin-hemoglobin complexsearch extracellular vesicular exosomesearch blood microparticlesearch cytosolsearch membranesearch endocytic vesicle lumensearch
B (P68871) iron ion bindingsearch oxygen transporter activitysearch protein bindingsearch metal ion bindingsearch heme bindingsearch oxygen bindingsearch hemoglobin bindingsearch peroxidase activitysearch haptoglobin bindingsearch small molecule metabolic processsearch regulation of blood vessel sizesearch renal absorptionsearch blood coagulationsearch platelet aggregationsearch bicarbonate transportsearch positive regulation of nitric oxide biosynthetic processsearch oxygen transportsearch regulation of blood pressuresearch protein heterooligomerizationsearch response to hydrogen peroxidesearch oxidation-reduction processsearch hydrogen peroxide catabolic processsearch positive regulation of cell deathsearch nitric oxide transportsearch transportsearch hemoglobin complexsearch extracellular regionsearch extracellular vesicular exosomesearch cytosolsearch endocytic vesicle lumensearch haptoglobin-hemoglobin complexsearch blood microparticlesearch

Chain InterPro annotation
A Globinsearch Haemoglobin, alphasearch Haemoglobin, pisearch Globin-likesearch Globin, structural domainsearch
B Globinsearch Haemoglobin, betasearch Globin-likesearch Globin, structural domainsearch