1ird Summary

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Crystal Structure of Human Carbonmonoxy-Haemoglobin at 1.25 A Resolution

A publication describing this structure is not available. The depositing authors are Park, S.-Y.search; Tame, J.R.H.search

This crystal structure was determined using X-ray diffraction at a resolution of 1.25 Å and deposited in 2001.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Hemoglobin alpha chain and Hemoglobin beta chain.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Hemoglobin alpha chain P69905 (2-142) (HBA_HUMAN)search Homo sapienssearch 98% 141 100%
B Hemoglobin beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P69905 (2 - 142) Hemoglobin alpha chain Homo sapiens
P68871 (2 - 147) Hemoglobin beta chain Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P69905) Globinssearch Globinssearch PF00042: Globinsearch
B (P68871) Globinssearch Globinssearch PF00042: Globinsearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A (P69905) oxygen bindingsearch protein bindingsearch haptoglobin bindingsearch iron ion bindingsearch heme bindingsearch peroxidase activitysearch oxygen transporter activitysearch metal ion bindingsearch extracellular vesicular exosomesearch membranesearch extracellular regionsearch endocytic vesicle lumensearch cytosolsearch hemoglobin complexsearch cytosolic small ribosomal subunitsearch haptoglobin-hemoglobin complexsearch blood microparticlesearch oxygen transportsearch bicarbonate transportsearch oxidation-reduction processsearch positive regulation of cell deathsearch response to hydrogen peroxidesearch hydrogen peroxide catabolic processsearch small molecule metabolic processsearch transportsearch protein heterooligomerizationsearch
B (P68871) protein bindingsearch oxygen transporter activitysearch iron ion bindingsearch haptoglobin bindingsearch hemoglobin bindingsearch peroxidase activitysearch oxygen bindingsearch metal ion bindingsearch heme bindingsearch haptoglobin-hemoglobin complexsearch extracellular vesicular exosomesearch cytosolsearch extracellular regionsearch hemoglobin complexsearch blood microparticlesearch endocytic vesicle lumensearch transportsearch response to hydrogen peroxidesearch positive regulation of cell deathsearch bicarbonate transportsearch hydrogen peroxide catabolic processsearch regulation of blood vessel sizesearch nitric oxide transportsearch oxygen transportsearch oxidation-reduction processsearch renal absorptionsearch small molecule metabolic processsearch regulation of blood pressuresearch blood coagulationsearch platelet aggregationsearch positive regulation of nitric oxide biosynthetic processsearch protein heterooligomerizationsearch

Chain InterPro annotation
A Globinsearch Haemoglobin, alphasearch Haemoglobin, pisearch Globin-likesearch Globin, structural domainsearch
B Globinsearch Haemoglobin, betasearch Globin-likesearch Globin, structural domainsearch