› 1io6

Solution NMR

GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 (GRB2) C-TERMINAL SH3 DOMAIN COMPLEXED WITH A LIGAND PEPTIDE (NMR, MINIMIZED MEAN STRUCTURE)

Released:
DOI: 10.2210/pdb1io6/pdb
PDB entry 1io6 coloured by chain, front view.
PDB entry 1io6 coloured by chain, side view.
PDB entry 1io6 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Kawasaki M, Ogura K, Hatanaka H, Inagaki F

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158855 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Growth factor receptor-bound protein 2 Chain: A
Molecule details ›
Chain: A
Length: 59 amino acids
Theoretical weight: 6.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P62993 (Residues: 159-215; Coverage: 26%)
Gene names: ASH, GRB2
Sequence domains: SH3 domain
Structure domains: SH3 Domains
A LIGAND PEPTIDE Chain: B
Molecule details ›
Chain: B
Length: 10 amino acids
Theoretical weight: 1.25 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

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