1ima Summary

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STRUCTURAL ANALYSIS OF INOSITOL MONOPHOSPHATASE COMPLEXES WITH SUBSTRATES

The structure was published by Bone, R., Frank, L., Springer, J.P., et al., Broughton, H.B., Baker, R., and Fletcher, S.R., in 1994 in a paper entitled "Structural analysis of inositol monophosphatase complexes with substrates." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 1994.

The experimental data on which the structure is based was not deposited.

This PDB entry contains multiple copies of the structure of INOSITOL MONOPHOSPHATASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A INOSITOL MONOPHOSPHATASE P29218 (1-277) (IMPA1_HUMAN)search Homo sapienssearch 100% 277 98%
B INOSITOL MONOPHOSPHATASE P29218 (1-277) (IMPA1_HUMAN)search Homo sapienssearch 100% 277 98%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P29218 (1 - 277) INOSITOL MONOPHOSPHATASE Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P29218) Inositol monophosphatase/fructose-1,6-bisphosphatase-likesearch Fructose-1,6-Bisphosphatase, subunit A, domain 1search, D-Maltodextrin-Binding Protein; domain 2search PF00459: Inositol monophosphatase familysearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A, B (P29218) phosphatidylinositol phosphorylationsearch phosphate-containing compound metabolic processsearch phosphatidylinositol biosynthetic processsearch inositol phosphate metabolic processsearch small molecule metabolic processsearch inositol phosphate dephosphorylationsearch inositol biosynthetic processsearch signal transductionsearch inositol monophosphate 4-phosphatase activitysearch inositol monophosphate 3-phosphatase activitysearch identical protein bindingsearch metal ion bindingsearch hydrolase activitysearch inositol monophosphate 1-phosphatase activitysearch protein homodimerization activitysearch inositol monophosphate phosphatase activitysearch cytosolsearch cytoplasmsearch extracellular vesicular exosomesearch

Chain InterPro annotation
A, B Inositol monophosphatasesearch Inositol monophosphatase, conserved sitesearch Inositol monophosphatase, Lithium-sensitivesearch Inositol monophosphatase, metal-binding sitesearch