Crystal Structure of Apo Human Pregnane X Receptor Ligand Binding Domain
The structure was published by Watkins, R.E., Wisely, G.B., Moore, L.B., et al., Willson, T.M., Kliewer, S.A., and Redinbo, M.R., in 2001 in a paper entitled "The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.52 Å and deposited in 2001.
The experimental data on which the structure is based was not deposited.
The PDB entry contains the structure of ORPHAN NUCLEAR RECEPTOR PXR. This molecule has the UniProt identifier O75469 (NR1I2_HUMAN). The sample contained 316 residues which is < 90% of the natural sequence. Out of 316 residues 263 were observed and are deposited in the PDB.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: