› 1ik5

X-ray diffraction
1.8Å resolution

Crystal Structure of a 14mer RNA Containing Double UU Bulges in Two Crystal Forms: A Novel U*(AU) Intramolecular Base Triple

Released:
DOI: 10.2210/pdb1ik5/pdb
PDB entry 1ik5 coloured by chain, front view.
PDB entry 1ik5 coloured by chain, side view.
PDB entry 1ik5 coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Crystal structures of two forms of a 14-mer RNA/DNA chimer duplex with double UU bulges: a novel intramolecular U*(A x U) base triple.
Deng J, Xiong Y, Sudarsanakumar C, Shi K, Sundaralingam M
RNA 7 1425-31 (2001)
PMID: 11680847

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196058 (preferred)
Entry contents:
2 distinct RNA molecules
Macromolecules (2 distinct):
5'-R(*GP*GP*UP*AP*UP*UP*UP*CP*GP*GP*UP*AP*(CBR)P*C)-3' Chain: A
Molecule details ›
Chain: A
Length: 14 nucleotides
Theoretical weight: 4.5 KDa
Source organism: Synthetic construct
Expression system: Not provided
5'-R(*GP*GP*UP*AP*UP*UP*UP*UP*GP*GP*UP*AP*(CBR)P*C)-3' Chain: B
Molecule details ›
Chain: B
Length: 14 nucleotides
Theoretical weight: 4.5 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand MG 2 x MG
1 modified residue:
Ligand CBR 2 x CBR

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: C2
Unit cell:
a: 60.04Å b: 29.53Å c: 52.44Å
α: 90° β: 120.83° γ: 90°
R-values:
R R work R free
0.209 0.209 0.232
Expression system: Not provided

Quick links

Citations

4 citation in other articles

Predicting RNA folding thermodynamics with a reduced chain representation model.
Cao et al. (2005)
3 more

1 mention without citation

Conformational readout of RNA by small ligands.
Kligun et al. (2013)