› 1ik0

Solution NMR

Solution Structure of Human IL-13

Released:
DOI: 10.2210/pdb1ik0/pdb
PDB entry 1ik0 coloured by chain, ensemble of 30 models, front view.
PDB entry 1ik0 coloured by chain, ensemble of 30 models, side view.
PDB entry 1ik0 coloured by chain, ensemble of 30 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of human IL-13 and implication for receptor binding.
Moy FJ, Diblasio E, Wilhelm J, Powers R
J Mol Biol 310 219-30 (2001)
PMID: 11419948

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152843 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interleukin-13 Chain: A
Molecule details ›
Chain: A
Length: 113 amino acids
Theoretical weight: 12.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P35225 (Residues: 35-146; Coverage: 92%)
Gene names: IL13, NC30
Sequence domains: Interleukin-13
Structure domains: Growth Hormone; Chain: A;

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

11 review citations

Alternative activation of macrophages: an immunologic functional perspective.
Martinez et al. (2009)
10 more

5 mentions without citation

Updates to the Integrated Protein-Protein Interaction Benchmarks: Docking Benchmark Version 5 and Affinity Benchmark Version 2.
Vreven et al. (2015)
4 more