1ijx Summary

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CRYSTAL STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF SECRETED FRIZZLED-RELATED PROTEIN 3 (SFRP-3;FZB)

The structure was published by Dann III, C.E., Hsieh, J.C., Rattner, A., Sharma, D., Nathans, J., and Leahy, D.J., in 2001 in a paper entitled "Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.9 Å and deposited in 2001.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of SECRETED FRIZZLED-RELATED SEQUENCE PROTEIN 3.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A SECRETED FRIZZLED-RELATED SEQUENCE PROTEIN 3 P97401 (33-157) (SFRP3_MOUSE)search Mus musculussearch < 90% 127 98%
B SECRETED FRIZZLED-RELATED SEQUENCE PROTEIN 3 P97401 (33-157) (SFRP3_MOUSE)search Mus musculussearch < 90% 127 98%
C SECRETED FRIZZLED-RELATED SEQUENCE PROTEIN 3 P97401 (33-157) (SFRP3_MOUSE)search Mus musculussearch < 90% 127 98%
D SECRETED FRIZZLED-RELATED SEQUENCE PROTEIN 3 P97401 (33-157) (SFRP3_MOUSE)search Mus musculussearch < 90% 127 98%
E SECRETED FRIZZLED-RELATED SEQUENCE PROTEIN 3 P97401 (33-157) (SFRP3_MOUSE)search Mus musculussearch < 90% 127 98%
F SECRETED FRIZZLED-RELATED SEQUENCE PROTEIN 3 P97401 (33-157) (SFRP3_MOUSE)search Mus musculussearch < 90% 127 98%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P97401 (33 - 157) SECRETED FRIZZLED-RELATED SEQUENCE PROTEIN 3 Mus musculus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B, C, D, E, F Frizzled cysteine-rich domainsearch Frizzled cysteine-rich domainsearch Fz domainsearch
Chain InterPro annotation
A, B, C, D, E, F Frizzled/secreted frizzled-related proteinsearch Frizzled domainsearch Secreted frizzled-related protein 3search