1ijq Summary


Crystal Structure of the LDL Receptor YWTD-EGF Domain Pair

The structure was published by Jeon, H., Meng, W., Takagi, J., Eck, M.J., Springer, T.A., and Blacklow, S.C., in 2001 in a paper entitled "Implications for familial hypercholesterolemia from the structure of the LDL receptor YWTD-EGF domain pair." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.5 Å and deposited in 2001.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of LOW-DENSITY LIPOPROTEIN RECEPTOR.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A LOW-DENSITY LIPOPROTEIN RECEPTOR P01130 (398-713) (LDLR_HUMAN)search Homo sapienssearch < 90% 316 97%
B LOW-DENSITY LIPOPROTEIN RECEPTOR P01130 (398-713) (LDLR_HUMAN)search Homo sapienssearch < 90% 316 97%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P01130 (398 - 713) LOW-DENSITY LIPOPROTEIN RECEPTOR Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B YWTD domainsearch, EGF-type modulesearch TolB, C-terminal domainsearch, Lamininsearch Low-density lipoprotein receptor repeat class Bsearch, Coagulation Factor Xa inhibitory sitesearch
Chain InterPro annotation
A, B LDLR class B repeatsearch Epidermal growth factor-like domainsearch Six-bladed beta-propeller, TolB-likesearch