Crystal Structure of Linoleic acid Bound in the Cyclooxygenase Channel of Prostaglandin Endoperoxide H Synthase-1.
The structure was published by Malkowski, M.G., Thuresson, E.D., Lakkides, K.M., et al., Micielli, R., Smith, W.L., and Garavito, R.M., in 2001 in a paper entitled "Structure of eicosapentaenoic and linoleic acids in the cyclooxygenase site of prostaglandin endoperoxide H synthase-1." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.9 Å and deposited in 2001.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Prostaglandin Endoperoxide H Synthase-1.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms homodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: