1ig7 Summary


Msx-1 Homeodomain/DNA Complex Structure

The structure was published by Hovde, S., Abate-Shen, C., and Geiger, J.H., in 2001 in a paper entitled "Crystal structure of the Msx-1 homeodomain/DNA complex" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.2 Å and deposited in 2001.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 3 biomacromolecules, namely 5'-D(*CP*AP*CP*TP*AP*AP*TP*TP*GP*AP*AP*GP*G)-3', 5'-D(P*TP*CP*CP*TP*TP*CP*AP*AP*TP*TP*AP*GP*TP*GP*AP*C)-3', and Homeotic protein Msx-1.

The molecule most likely forms heterotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Homeotic protein Msx-1 P13297 (173-230) (MSX1_MOUSE)search Mus musculussearch < 90% 58 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P13297 (173 - 230) Homeotic protein Msx-1 Mus musculus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Homeodomainsearch Homeodomain-likesearch Homeobox domainsearch

Chain ID Molecular function (GO) Biological process (GO)
A (P13297) sequence-specific DNA bindingsearch DNA bindingsearch regulation of transcription, DNA-templatedsearch

Chain InterPro annotation
A Helix-turn-helix motifsearch Homeobox domainsearch Homeodomain-likesearch Homeobox, conserved sitesearch Homeodomain, metazoasearch