› 1ido

X-ray diffraction
1.7Å resolution

I-DOMAIN FROM INTEGRIN CR3, MG2+ BOUND

Released:
DOI: 10.2210/pdb1ido/pdb
PDB entry 1ido coloured by chain, front view.
PDB entry 1ido coloured by chain, side view.
PDB entry 1ido coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18).
Lee JO, Rieu P, Arnaout MA, Liddington R
Cell 80 631-8 (1995)
PMID: 7867070

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145707 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Integrin alpha-M Chain: A
Molecule details ›
Chain: A
Length: 189 amino acids
Theoretical weight: 21.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P11215 (Residues: 143-331; Coverage: 17%)
Gene names: CD11B, CR3A, ITGAM
Sequence domains: von Willebrand factor type A domain
Structure domains: von Willebrand factor, type A domain

Ligands and Environments

1 bound ligand:
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P43
Unit cell:
a: 45.7Å b: 45.7Å c: 94.3Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.202 0.202 not available
Expression system: Escherichia coli

Quick links

Citations

117 review citations

Integrins: bidirectional, allosteric signaling machines.
Hynes RO. (2002)
116 more

41 mentions without citation

Structural basis of integrin regulation and signaling.
Luo et al. (2007)
40 more