1iah Summary

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CRYSTAL STRUCTURE OF THE ATYPICAL PROTEIN KINASE DOMAIN OF A TRP CA-CHANNEL, CHAK (ADP-MG COMPLEX)

The structure was published by Yamaguchi, H., Matsushita, M., Nairn, A.C., and Kuriyan, J., in 2001 in a paper entitled "Crystal structure of the atypical protein kinase domain of a TRP channel with phosphotransferase activity." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.4 Å and deposited in 2001.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of TRANSIENT RECEPTOR POTENTIAL-RELATED PROTEIN.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A TRANSIENT RECEPTOR POTENTIAL-RELATED PROTEIN Q923J1 (1549-1828) (TRPM7_MOUSE)search Mus musculussearch < 90% 280 100%
B TRANSIENT RECEPTOR POTENTIAL-RELATED PROTEIN Q923J1 (1549-1828) (TRPM7_MOUSE)search Mus musculussearch < 90% 280 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q923J1 (1549 - 1828) TRANSIENT RECEPTOR POTENTIAL-RELATED PROTEIN Mus musculus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B MHCK/EF2 kinasesearch Phosphorylase Kinase; domain 1search Alpha-kinase familysearch

Chain ID Biological process (GO) Cellular component (GO) Molecular function (GO)
A, B (Q923J1) cation transportsearch protein phosphorylationsearch cellular magnesium ion homeostasissearch integral component of membranesearch transferase activity, transferring phosphorus-containing groupssearch protein serine/threonine kinase activitysearch ATP bindingsearch

Chain InterPro annotation
A, B MHCK/EF2 kinasesearch Protein kinase-like domainsearch Transient receptor potential cation channel subfamily M member 7search