1i3z Summary

pdbe.org/1i3z
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MURINE EAT2 SH2 DOMAIN IN COMPLEX WITH SLAM PHOSPHOPEPTIDE

The structure was published by Morra, M., Lu, J., Poy, F., et al., Engel, P., Eck, M.J., and Terhorst, C., in 2001 in a paper entitled "Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.15 Å and deposited in 2001.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely EWS/FLI1 ACTIVATED TRANSCRIPT 2 and SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A EWS/FLI1 ACTIVATED TRANSCRIPT 2 O35324 (1-103) (SH21B_MOUSE)search Mus musculussearch < 90% 103 100%
B SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE Q13291 (273-286) (SLAF1_HUMAN)search Homo sapienssearch < 90% 14 71%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
O35324 (1 - 103) EWS/FLI1 ACTIVATED TRANSCRIPT 2 Mus musculus
Q13291 (273 - 286) SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A SH2 domainsearch SHC Adaptor Proteinsearch SH2 domainsearch
B
Chain InterPro annotation
A SH2 domainsearch
B