› 1i3h

X-ray diffraction
1.2Å resolution

CONCANAVALIN A-DIMANNOSE STRUCTURE

Released:
DOI: 10.2210/pdb1i3h/pdb
PDB entry 1i3h coloured by chain, front view.
PDB entry 1i3h coloured by chain, side view.
PDB entry 1i3h coloured by chain, top view.
Source organism: Canavalia ensiformis
Primary publication:
The 1.2 A resolution structure of the Con A-dimannose complex.
Sanders DA, Moothoo DN, Raftery J, Howard AJ, Helliwell JR, Naismith JH
J Mol Biol 310 875-84 (2001)
PMID: 11453694

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136271 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Concanavalin-A, 2nd part Chain: A
Molecule details ›
Chain: A
Length: 237 amino acids
Theoretical weight: 25.62 KDa
Source organism: Canavalia ensiformis
UniProt:
  • Canonical: P02866 (Residues: 28-148; Coverage: 46%)
Sequence domains: Legume lectin domain
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: MAN
Carbohydrate polymer
2 bound ligands:
Ligand MN 1 x MN
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ENRAF-NONIUS, APS BEAMLINE 17-ID
Spacegroup: I222
Unit cell:
a: 90.9Å b: 86.41Å c: 65.42Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.17 0.167 0.19

Quick links

Citations

1 review citation

Carbohydrate-mimetic peptides: structural aspects of mimicry and therapeutic implications.
Agostino et al. (2011)
16 other articles

7 mentions without citation

Overview of the Structure⁻Function Relationships of Mannose-Specific Lectins from Plants, Algae and Fungi.
Barre et al. (2019)
6 more