1hz8 Summary

pdbe.org/1hz8
spacer

SOLUTION STRUCTURE AND BACKBONE DYNAMICS OF A CONCATEMER OF EGF-HOMOLOGY MODULES OF THE HUMAN LOW DENSITY LIPOPROTEIN RECEPTOR

The structure was published by Kurniawan, N.D., Aliabadizadeh, K., Brereton, I.M., Kroon, P.A., and Smith, R., in 2001 in a paper entitled "NMR structure and backbone dynamics of a concatemer of epidermal growth factor homology modules of the human low-density lipoprotein receptor." (abstract).

The structure was determined using NMR spectroscopy and deposited in 2001.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of LOW DENSITY LIPOPROTEIN RECEPTOR. This molecule has the UniProt identifier P01130 (LDLR_HUMAN)search. The sample contained 82 residues which is < 90% of the natural sequence. Out of 82 residues 82 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A LOW DENSITY LIPOPROTEIN RECEPTOR P01130 (314-395) (LDLR_HUMAN)search Homo sapienssearch < 90% 82 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P01130 (314 - 395) LOW DENSITY LIPOPROTEIN RECEPTOR Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH)
A EGF-type modulesearch Lamininsearch

Chain ID Molecular function (GO)
A (P01130) calcium ion bindingsearch

Chain InterPro annotation
A EGF-type aspartate/asparagine hydroxylation sitesearch Epidermal growth factor-like domainsearch EGF-like calcium-binding domainsearch Insulin-like growth factor binding protein, N-terminalsearch EGF-like, conserved sitesearch EGF-like calcium-binding, conserved sitesearch