› 1hyk

Solution NMR

AGOUTI-RELATED PROTEIN (87-132) (AC-AGRP(87-132))

Released:
DOI: 10.2210/pdb1hyk/pdb
PDB entry 1hyk coloured by chain, ensemble of 40 models, front view.
PDB entry 1hyk coloured by chain, ensemble of 40 models, side view.
PDB entry 1hyk coloured by chain, ensemble of 40 models, top view.
Source organism: Homo sapiens
Primary publication:
NMR structure of a minimized human agouti related protein prepared by total chemical synthesis.
Bolin KA, Anderson DJ, Trulson JA, Thompson DA, Wilken J, Kent SB, Gantz I, Millhauser GL
FEBS Lett 451 125-31 (1999)
PMID: 10371151

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126197 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Agouti-related protein Chain: A
Molecule details ›
Chain: A
Length: 46 amino acids
Theoretical weight: 5.21 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O00253 (Residues: 87-132; Coverage: 41%)
Gene names: AGRP, AGRT, ART
Sequence domains: Agouti protein
Structure domains: Agouti domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

Quick links

Citations

12 review citations

Synthesis of native proteins by chemical ligation.
Dawson et al. (2000)
11 more

13 mentions without citation

Protein scaffold-based molecular probes for cancer molecular imaging.
Miao et al. (2011)
12 more