1hqc Summary



The structure was published by Yamada, K., Kunishima, N., Mayanagi, K., et al., Iwasaki, H., Shinagawa, H., and Morikawa, K., in 2001 in a paper entitled "Crystal structure of the Holliday junction migration motor protein RuvB from Thermus thermophilus HB8." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 3.2 Å and deposited in 2000.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of RUVB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A RUVB Q5SL87 (1-324) (RUVB_THET8)search Thermus thermophilus HB8search 96% 324 96%
B RUVB Q5SL87 (1-324) (RUVB_THET8)search Thermus thermophilus HB8search 96% 324 96%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q5SL87 (1 - 324) RUVB Thermus thermophilus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (Q5SL87) Helicase DNA-binding domainsearch, Extended AAA-ATPase domainsearch P-loop containing nucleotide triphosphate hydrolasessearch, Helicase, Ruva Protein; domain 3search, "winged helix" repressor DNA binding domainsearch PF05491: Holliday junction DNA helicase ruvB C-terminussearch, PF05496: Holliday junction DNA helicase ruvB N-terminussearch

Chain ID Biological process (GO) Molecular function (GO)
A, B (Q5SL87) DNA recombinationsearch DNA repairsearch DNA duplex unwindingsearch SOS responsesearch cellular response to DNA damage stimulussearch DNA bindingsearch four-way junction helicase activitysearch ATP bindingsearch hydrolase activitysearch helicase activitysearch nucleotide bindingsearch

Chain InterPro annotation
A, B AAA+ ATPase domainsearch DNA helicase, Holliday junction RuvB typesearch DNA helicase, Holliday junction RuvB type, C-terminalsearch DNA helicase, Holliday junction RuvB type, N-terminalsearch Winged helix-turn-helix DNA-binding domainsearch P-loop containing nucleoside triphosphate hydrolasesearch