1hpl Summary

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HORSE PANCREATIC LIPASE. THE CRYSTAL STRUCTURE AT 2.3 ANGSTROMS RESOLUTION

The structure was published by Bourne, Y., Martinez, C., Kerfelec, B., Lombardo, D., Chapus, C., and Cambillau, C., in 1994 in a paper entitled "Horse pancreatic lipase. The crystal structure refined at 2.3 A resolution." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 1993.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of LIPASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A LIPASE P29183 (13-461) (LIPP_HORSE)search Equus caballussearch 100% 449 100%
B LIPASE P29183 (13-461) (LIPP_HORSE)search Equus caballussearch 100% 449 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P29183 (13 - 461) LIPASE Equus caballus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P29183) Colipase-binding domainsearch, Pancreatic lipase, N-terminal domainsearch Rossmann foldsearch, Lipoxygenase-1search PF00151: Lipasesearch, PF01477: PLAT/LH2 domainsearch

Chain ID Biological process (GO) Cellular component (GO) Molecular function (GO)
A, B (P29183) lipid metabolic processsearch intestinal cholesterol absorptionsearch lipid catabolic processsearch extracellular regionsearch hydrolase activitysearch catalytic activitysearch triglyceride lipase activitysearch metal ion bindingsearch

Chain InterPro annotation
A, B Triacylglycerol lipase familysearch PLAT/LH2 domainsearch Pancreatic lipasesearch Lipase/lipooxygenase, PLAT/LH2search Lipase, N-terminalsearch Lipase, LIPH-typesearch Alpha/Beta hydrolase foldsearch