1hja Summary

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LYS 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH ALPHA-CHYMOTRYPSIN

A publication describing this structure is not available. The depositing authors are Ding, J.-H.search; James, M.N.G.search

This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 1997.

The experimental data on which the structure is based was also deposited.

This entry contains 8 copies of 4 unique biopolymers (complete list).

The molecule most likely forms heterotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A ALPHA-CHYMOTRYPSIN P00767 (1-13) (CTRB_BOVIN)search Bos taurussearch < 90% 13 76%
B ALPHA-CHYMOTRYPSIN P00766 (16-146) (CTRA_BOVIN)search Bos taurussearch 94% 131 100%
C ALPHA-CHYMOTRYPSIN P00766 (149-245) (CTRA_BOVIN)search Bos taurussearch 94% 97 100%
I OVOMUCOID INHIBITOR P68390 (135-185) (IOVO_MELGA)search Meleagris gallopavosearch 100% 51 100%


This entry contains 3 unique UniProt proteins:

UniProt accession Name Organism PDB
P00767 (1 - 13) ALPHA-CHYMOTRYPSIN Bos taurus
P00766 (16 - 146) ALPHA-CHYMOTRYPSIN Bos taurus
P68390 (135 - 185) OVOMUCOID INHIBITOR Meleagris gallopavo

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Eukaryotic proteasessearch
B (P00766) Eukaryotic proteasessearch Trypsin-like serine proteasessearch PF00089: Trypsinsearch
C (P00766) Eukaryotic proteasessearch Trypsin-like serine proteasessearch PF00089: Trypsinsearch
I (P68390) Ovomucoid domain III-likesearch Wheat Germ Agglutinin (Isolectin 2); domain 1search PF00050: Kazal-type serine protease inhibitor domainsearch

Chain ID Biological process (GO) Molecular function (GO)
B (P00766) proteolysissearch serine-type endopeptidase activitysearch catalytic activitysearch
C (P00766) proteolysissearch catalytic activitysearch serine-type endopeptidase activitysearch
I (P68390) serine-type endopeptidase inhibitor activitysearch

Chain InterPro annotation
A
B Peptidase S1search Peptidase S1A, chymotrypsin-typesearch Trypsin-like cysteine/serine peptidase domainsearch Peptidase S1, trypsin family, active sitesearch
C Peptidase S1search Trypsin-like cysteine/serine peptidase domainsearch Peptidase S1, trypsin family, active sitesearch
I Proteinase inhibitor I1, Kazal metazoasearch Kazal domainsearch