1hj7 Summary

pdbe.org/1hj7
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NMR study of a pair of LDL receptor Ca2+ binding epidermal growth factor-like domains, 20 structures

The structure was published by Saha, S., Boyd, J., Werner, J.M., et al., Handford, P.A., Campbell, I.D., and Downing, A.K., in 2001 in a paper entitled "Solution Structure of the Ldl Receptor Egf-Ab Pair: A Paradigm for the Assembly of Tandem Calcium Binding Egf Domains" (abstract).

The structure was determined using NMR spectroscopy and deposited in 2001.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of LDL RECEPTOR. This molecule has the UniProt identifier P01130 (LDLR_HUMAN)search. The sample contained 80 residues which is < 90% of the natural sequence. Out of 80 residues 80 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A LDL RECEPTOR P01130 (314-393) (LDLR_HUMAN)search Homo sapienssearch < 90% 80 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P01130 (314 - 393) LDL RECEPTOR Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH)
A EGF-type modulesearch Lamininsearch

Chain ID Molecular function (GO)
A (P01130) calcium ion bindingsearch

Chain InterPro annotation
A EGF-type aspartate/asparagine hydroxylation sitesearch Epidermal growth factor-like domainsearch EGF-like calcium-binding domainsearch Insulin-like growth factor binding protein, N-terminalsearch EGF-like, conserved sitesearch EGF-like calcium-binding, conserved sitesearch