1hj1 Summary



The structure was published by Pike, A.C.W., Brzozowski, A.M., Walton, J., et al., Li, Y.L., Gustafsson, J.A., and Carlquist, M., in 2001 in a paper entitled "Structural Insights Into the Mode of Action of a Pure Antiestrogen" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 2001.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of OESTROGEN RECEPTOR BETA. This molecule has the UniProt identifier Q62986 (ESR2_RAT)search. The sample contained 255 residues which is < 90% of the natural sequence. Out of 255 residues 200 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A OESTROGEN RECEPTOR BETA Q62986 (255-509) (ESR2_RAT)search Rattus norvegicussearch < 90% 255 80%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q62986 (255 - 509) OESTROGEN RECEPTOR BETA Rattus norvegicus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Nuclear receptor ligand-binding domainsearch Retinoid X Receptorsearch Ligand-binding domain of nuclear hormone receptorsearch

Chain ID Cellular component (GO) Molecular function (GO) Biological process (GO)
A (Q62986) nucleussearch steroid hormone receptor activitysearch DNA bindingsearch sequence-specific DNA binding transcription factor activitysearch regulation of transcription, DNA-templatedsearch steroid hormone mediated signaling pathwaysearch

Chain InterPro annotation
A Nuclear hormone receptor, ligand-binding, coresearch Steroid hormone receptorsearch Nuclear hormone receptor, ligand-bindingsearch