1hcs Summary

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NMR STRUCTURE OF THE HUMAN SRC SH2 DOMAIN COMPLEX

The structure was published by Xu, R.X., Word, J.M., Davis, D.G., Rink, M.J., Willard Jr., D.H., and Gampe Jr., R.T., in 1995 in a paper entitled "Solution structure of the human pp60c-src SH2 domain complexed with a phosphorylated tyrosine pentapeptide." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1994.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely ACETYL-PYEEIE-OH and HUMAN SRC.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
B HUMAN SRC P12931 (144-249) (SRC_HUMAN)search Homo sapienssearch 100% 107 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P12931 (144 - 249) HUMAN SRC Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
B (P12931) SH2 domainsearch SHC Adaptor Proteinsearch PF00017: SH2 domainsearch
Chain InterPro annotation
B SH2 domainsearch