Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140714 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Phosphatidylinositol 3-kinase regulatory subunit alpha
Molecule details ›
Chain: A
Length: 112 amino acids
Theoretical weight: 12.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: SH2 domain
Structure domains: SH2 domain
Length: 112 amino acids
Theoretical weight: 12.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P27986 (Residues: 616-724; Coverage: 15%)
Sequence domains: SH2 domain
Structure domains: SH2 domain
Platelet-derived growth factor receptor beta
Molecule details ›
Chain: B
Length: 5 amino acids
Theoretical weight: 702 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 5 amino acids
Theoretical weight: 702 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P09619 (Residues: 751-755; Coverage: 1%)
