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1h2s Summary pdbe.org/1h2s
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PDB entry 1h2s

MOLECULAR BASIS OF TRANSMENBRANE SIGNALLING BY SENSORY RHODOPSIN II-TRANSDUCER COMPLEX

The structure was published by Gordeliy, V.I., Labahn, J., Moukhametzianov, R., et al., Scheidig, A., Klare, J.P., and Engelhard, M., in 2002 in a paper entitled "Molecular Basis of Transmembrane Signalling by Sensory Rhodopsin II-Transducer Complex" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.93 Å and deposited in 2002.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely SENSORY RHODOPSIN II and SENSORY RHODOPSIN II TRANSDUCER.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A SENSORY RHODOPSIN II P42196 (1-225) (BACS2_NATPH)search Natronomonas pharaonissearch 91% 225 100%
B SENSORY RHODOPSIN II TRANSDUCER P42259 (23-82) (HTR2_NATPH)search Natronomonas pharaonissearch < 90% 60 100%

This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P42196 (1 - 225) SENSORY RHODOPSIN II Natronomonas pharaonis
P42259 (23 - 82) SENSORY RHODOPSIN II TRANSDUCER Natronomonas pharaonis

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P42196) Bacteriorhodopsin-likesearch Rhopdopsin 7-helix transmembrane proteinssearch Bacteriorhodopsin-like proteinsearch
B Htr2 transmembrane domain-likesearch Helix hairpin binsearch HAMP domainsearch, Methyl-accepting chemotaxis protein (MCP) signaling domainsearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A (P42196) Receptor activitysearch, Ion channel activitysearch, Photoreceptor activitysearch Plasma membranesearch, Membranesearch, Integral to membranesearch Ion transportsearch, Phototransductionsearch, Protein-chromophore linkagesearch, Response to stimulussearch

Chain InterPro annotation
A Rhodopsin, archaeal/bacterial/fungalsearch, Rhodopsin, retinal binding sitesearch
B HAMP linker domainsearch, Chemotaxis methyl-accepting receptor, signallingsearch, Chemotaxis methyl-accepting receptorsearch