STRUCTURE OF HUMAN THR160-PHOSPHO CDK2/CYCLIN A COMPLEXED WITH THE INHIBITOR NU2058
The structure was published by Davies, T.G., Bentley, J., Arris, C.E., et al., Tucker, J.A., Wang, L., and Whitfield, H.J., in 2002 in a paper entitled "Structure-Based Design of a Potent Purine-Based Cyclin-Dependent Kinase Inhibitor" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.1 Å and deposited in 2002.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely CELL DIVISION PROTEIN KINASE 2 and CYCLIN A2.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: