› 1h0j

X-ray diffraction
1.9Å resolution

Structural Basis of the Membrane-induced Cardiotoxin A3 Oligomerization

Released:
DOI: 10.2210/pdb1h0j/pdb
PDB entry 1h0j coloured by chain, front view.
PDB entry 1h0j coloured by chain, side view.
PDB entry 1h0j coloured by chain, top view.
Source organism: Naja atra
Primary publication:
Structural basis of membrane-induced cardiotoxin A3 oligomerization.
Forouhar F, Huang WN, Liu JH, Chien KY, Wu WG, Hsiao CD
J Biol Chem 278 21980-8 (2003)
PMID: 12660250

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157992 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytotoxin 3 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 60 amino acids
Theoretical weight: 6.76 KDa
Source organism: Naja atra
UniProt:
  • Canonical: P60301 (Residues: 22-81; Coverage: 100%)
Structure domains: CD59

Ligands and Environments

1 bound ligand:
Ligand SDS 10 x SDS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P21212
Unit cell:
a: 74.902Å b: 76.202Å c: 47.784Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.227 0.227 0.28

Quick links

Citations

8 review citations

Myotoxic phospholipases A2 and the regeneration of skeletal muscles.
Harris JB. (2003)
7 more

5 mentions without citation

The role of hydrophobic interactions in positioning of peripheral proteins in membranes.
Lomize et al. (2007)
4 more