PDB entry 1h0a

EPSIN ENTH BOUND TO INS(1,4,5)P3

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The structure was published by Ford, M.G.J., Mills, I., Peter, B., et al., Praefcke, G., Evans, P.R., and Mcmahon, H.T., in 2002 in a paper entitled "Curvature of Clathrin-Coated Pits Driven by Epsin" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.7 Å and deposited in 2002.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of EPSIN. This molecule has the UniProt identifier O88339 (EPN1_RAT). The sample contained 158 residues which is < 90% of the natural sequence. Out of 158 residues 157 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain	Name	UniProt	Name of source organism	% of UniProt sequence present in the sample	Residues in the sample molecules	% of residues observed
A	EPSIN	O88339 (1-158) (EPN1_RAT)	Rattus norvegicus	< 90%	158	100%

This entry contains 1 unique UniProt protein:

UniProt accession	Name	Organism	PDB
O88339 (1 - 158)	EPSIN	Rattus norvegicus	Related PDB sequences UniProt coverage

Chain	Structural classification (SCOP)	Structural classification (CATH)	Sequence family (Pfam)
A	ENTH domain	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat	ENTH domain, Ubiquitin interaction motif

Chain	InterPro annotation
A	Epsin domain, N-terminal, Ubiquitin interacting motif, ENTH/VHS, Epsin-like, N-terminal