1guj Summary

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INSULIN AT PH 2: STRUCTURAL ANALYSIS OF THE CONDITIONS PROMOTING INSULIN FIBRE FORMATION.

The structure was published by Whittingham, J.L., Scott, D.J., Chance, K., et al., Finch, J., Brange, J., and Dodson, G.G., in 2002 in a paper entitled "Insulin at Ph2: Structural Analysis of the Conditions Promoting Insulin Fibre Formation" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.62 Å and deposited in 2002.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely INSULIN.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A INSULIN P01308 (90-110) (INS_HUMAN)search Homo sapienssearch 100% 21 100%
C INSULIN P01308 (90-110) (INS_HUMAN)search Homo sapienssearch 100% 21 100%
B INSULIN P01308 (25-54) (INS_HUMAN)search Homo sapienssearch 100% 30 100%
D INSULIN P01308 (25-54) (INS_HUMAN)search Homo sapienssearch 100% 30 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P01308 (90 - 110) INSULIN Homo sapiens

Chain Structural classification (SCOP) Sequence family (Pfam)
A, C (P01308) Insulin-likesearch PF00049: Insulin/IGF/Relaxin familysearch
B, D (P01308) Insulin-likesearch PF00049: Insulin/IGF/Relaxin familysearch

Chain ID Molecular function (GO) Cellular component (GO)
A, C (P01308) hormone activitysearch extracellular regionsearch
B, D (P01308) hormone activitysearch extracellular regionsearch

Chain InterPro annotation
A, C Insulin-likesearch Insulin, conserved sitesearch
B, D Insulinsearch Insulin-likesearch