Function and Biology

b-glucosidase from Streptomyces sp

Source organism: Streptomyces sp.
Biochemical function: scopolin beta-glucosidase activity
Biological process: cellulose catabolic process
Cellular component: cytosol

EC 3.2.1.21: Beta-glucosidase

Reaction catalysed:
Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose
Systematic name:
Beta-D-glucoside glucohydrolase
Alternative Name(s):
  • Amygdalase
  • Amygdalinase
  • Arbutinase
  • Aryl-beta-glucosidase
  • Beta-1,6-glucosidase
  • Beta-D-glucosidase
  • Beta-glucoside glucohydrolase
  • Cellobiase
  • Elaterase
  • Emulsin
  • Gentiobiase
  • Gentobiase
  • Limarase
  • Primeverosidase
  • Salicilinase
  • p-nitrophenyl beta-glucosidase

Sequence family

Pfam Protein family (Pfam)
PF00232
Domain description: Glycosyl hydrolase family 1
Occurring in:
  1. Beta-glucosidase
The deposited structure of PDB entry 1gon contains 2 copies of Pfam domain PF00232 (Glycosyl hydrolase family 1) in Beta-glucosidase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001360
Domain description: Glycoside hydrolase family 1
Occurring in:
  1. Beta-glucosidase
IPR018120
Domain description: Glycoside hydrolase family 1, active site
Occurring in:
  1. Beta-glucosidase
IPR033132
Domain description: Glycosyl hydrolases family 1, N-terminal conserved site
Occurring in:
  1. Beta-glucosidase
IPR017736
Domain description: Glycoside hydrolase, family 1, beta-glucosidase
Occurring in:
  1. Beta-glucosidase
IPR017853
Domain description: Glycoside hydrolase superfamily
Occurring in:
  1. Beta-glucosidase

Structure domain

CATH CATH domain
3.20.20.80
Class: Alpha Beta
Architecture: Alpha-Beta Barrel
Topology: TIM Barrel
Homology: Glycosidases
Occurring in:
  1. Beta-glucosidase
The deposited structure of PDB entry 1gon contains 2 copies of CATH domain 3.20.20.80 (TIM Barrel) in Beta-glucosidase. Showing 1 copy in chain A.
SCOP SCOP annotation
51521
Class: Alpha and beta proteins (a/b)
Fold: TIM beta/alpha-barrel
Superfamily: (Trans)glycosidases
Occurring in:
  1. Beta-glucosidase
The deposited structure of PDB entry 1gon contains 2 copies of SCOP domain 51521 (Family 1 of glycosyl hydrolase) in Beta-glucosidase. Showing 1 copy in chain A.