› 1gnu

X-ray diffraction
1.75Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131847 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gamma-aminobutyric acid receptor-associated protein Chain: A
Molecule details ›
Chain: A
Length: 117 amino acids
Theoretical weight: 13.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O95166 (Residues: 1-117; Coverage: 100%)
Gene names: FLC3B, GABARAP, HT004
Sequence domains: Autophagy protein Atg8 ubiquitin like
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

1 bound ligand:
Ligand NI 1 x NI
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX14.1
Spacegroup: P212121
Unit cell:
a: 30.013Å b: 55.124Å c: 64.418Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.203 0.201 0.23
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

8 review citations

GABAA receptor trafficking-mediated plasticity of inhibitory synapses.
Luscher et al. (2011)
7 more

35 mentions without citation

Emerging degrader technologies engaging lysosomal pathways.
Ding et al. (2022)
34 more