1glu Summary



The structure was published by Luisi, B.F., Xu, W.X., Otwinowski, Z., Freedman, L.P., Yamamoto, K.R., and Sigler, P.B., in 1991 in a paper entitled "Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.9 Å and deposited in 1992.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*TP*CP*GP*AP*TP*GP*TP*TP*C P*TP*G)-3') and PROTEIN (GLUCOCORTICOID RECEPTOR).

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A PROTEIN (GLUCOCORTICOID RECEPTOR) P06536 (440-514) (GCR_RAT)search Rattus norvegicussearch < 90% 81 100%
B PROTEIN (GLUCOCORTICOID RECEPTOR) P06536 (440-514) (GCR_RAT)search Rattus norvegicussearch < 90% 81 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P06536 (440 - 514) PROTEIN (GLUCOCORTICOID RECEPTOR) Rattus norvegicus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B Nuclear receptorsearch Erythroid Transcription Factor GATA-1, subunit Asearch Zinc finger, C4 type (two domains)search

Chain ID Cellular component (GO) Molecular function (GO) Biological process (GO)
A, B (P06536) nucleussearch calcitriol receptor activitysearch DNA bindingsearch zinc ion bindingsearch sequence-specific DNA bindingsearch sequence-specific DNA binding transcription factor activitysearch regulation of transcription, DNA-templatedsearch

Chain InterPro annotation
A, B Zinc finger, nuclear hormone receptor-typesearch Zinc finger, NHR/GATA-typesearch