1gl9 Summary



The structure was published by Rodriguez, A.C. and Stock, D., in 2002 in a paper entitled "Crystal Structure of Reverse Gyrase: Insights Into the Positive Supercoiling of DNA." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 3.2 Å and deposited in 2001.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of REVERSE GYRASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
B REVERSE GYRASE O29238 (1-1054) (RGYR_ARCFU)search Archaeoglobus fulgidus DSM 4304search 97% 1054 96%
C REVERSE GYRASE O29238 (1-1054) (RGYR_ARCFU)search Archaeoglobus fulgidus DSM 4304search 97% 1054 96%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
O29238 (1 - 1054) REVERSE GYRASE Archaeoglobus fulgidus DSM 4304

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
B, C (O29238) Helicase-like "domain" of reverse gyrasesearch, Prokaryotic type I DNA topoisomerasesearch P-loop containing nucleotide triphosphate hydrolasessearch, Rossmann foldsearch, Topoisomerase I, domain 2search, Topoisomerase I, domain 4search PF00270: DEAD/DEAH box helicasesearch, PF01131: DNA topoisomerasesearch, PF01751: Toprim domainsearch

Chain ID Molecular function (GO) Biological process (GO)
B, C (O29238) DNA topoisomerase activitysearch DNA bindingsearch ATP bindingsearch nucleic acid bindingsearch magnesium ion bindingsearch hydrolase activitysearch helicase activitysearch nucleotide bindingsearch zinc ion bindingsearch isomerase activitysearch DNA topoisomerase type II (ATP-hydrolyzing) activitysearch DNA topoisomerase type I activitysearch metal ion bindingsearch DNA topological changesearch ATP catabolic processsearch DNA unwinding involved in DNA replicationsearch

Chain InterPro annotation
B, C DNA topoisomerase, type IAsearch DNA topoisomerase, type IA, domain 2search DNA topoisomerase, type IA, DNA-binding domainsearch Reverse gyrasesearch Toprim domainsearch DEAD/DEAH box helicase domainsearch DNA topoisomerase, type IA, centralsearch DNA topoisomerase, type IA, central region, subdomain 1search DNA topoisomerase, type IA, central region, subdomain 3search Helicase superfamily 1/2, ATP-binding domainsearch DNA topoisomerase, type IA, core domainsearch P-loop containing nucleoside triphosphate hydrolasesearch