1ggt Summary



The structure was published by Yee, V.C., Pedersen, L.C., Le Trong, I., Bishop, P.D., Stenkamp, R.E., and Teller, D.C., in 1994 in a paper entitled "Three-dimensional structure of a transglutaminase: human blood coagulation factor XIII." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.65 Å and deposited in 1994.

The experimental data on which the structure is based was not deposited.

This PDB entry contains multiple copies of the structure of COAGULATION FACTOR XIII.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A COAGULATION FACTOR XIII P00488 (2-732) (F13A_HUMAN)search Homo sapienssearch 100% 731 97%
B COAGULATION FACTOR XIII P00488 (2-732) (F13A_HUMAN)search Homo sapienssearch 100% 731 97%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P00488 (2 - 732) COAGULATION FACTOR XIII Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P00488) Transglutaminase N-terminal domainsearch, Transglutaminase, two C-terminal domainssearch, Transglutaminase coresearch Immunoglobulinssearch, Coagulation Factor XIII, subunit A, domain 2search PF00868: Transglutaminase familysearch, PF00927: Transglutaminase family, C-terminal ig like domainsearch, PF01841: Transglutaminase-like superfamilysearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A, B (P00488) peptide cross-linkingsearch blood coagulationsearch platelet degranulationsearch platelet activationsearch hemostasissearch protein-glutamine gamma-glutamyltransferase activitysearch transferase activity, transferring acyl groupssearch transferase activitysearch metal ion bindingsearch extracellular regionsearch cytoplasmsearch blood microparticlesearch platelet alpha granule lumensearch

Chain InterPro annotation
A, B Transglutaminase, N-terminalsearch Transglutaminase-likesearch Transglutaminase, C-terminalsearch Immunoglobulin-like foldsearch Transglutaminase, conserved sitesearch Immunoglobulin E-setsearch Protein-glutamine gamma-glutamyltransferase, eukaryotasearch