1gfc Summary

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SOLUTION STRUCTURE AND LIGAND-BINDING SITE OF THE C-TERMINAL SH3 DOMAIN OF GRB2

The structure was published by Kohda, D., Terasawa, H., Ichikawa, S., et al., Ullrich, A., Schlessinger, J., and Inagaki, F., in 1994 in a paper entitled "Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1994.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2. This molecule has the UniProt identifier P62993 (GRB2_HUMAN)search. The sample contained 59 residues which is < 90% of the natural sequence. Out of 59 residues 59 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 P62993 (159-215) (GRB2_HUMAN)search Homo sapienssearch 100% 59 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P62993 (159 - 215) GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P62993) SH3-domainsearch SH3 Domainssearch PF00018: SH3 domainsearch
Chain InterPro annotation
A SH3 domainsearch