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EBI PDBe PDBeView

PDBe Entry: 1gar view

TOWARDS STRUCTURE-BASED DRUG DESIGN: CRYSTAL STRUCTURE OF A MULTISUBSTRATE ADDUCT COMPLEX OF GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE AT 1.96 ANGSTROMS RESOLUTION
Summary
Header TRANSFERASE (FORMYL)search
Method X-RAY DIFFRACTION
Experiment Resolution: 1.96 Å, R-factor: 16.8%, Free R-factor: 29.0%, Spacegroup: P 1 21 1
Released 10/07/1995, deposition: 08/12/1994, last revision: 24/02/2009
Authors Wilson, I.A.search; Klein, C.search; Chen, P.search; Arevalo, J.H.search
Primary citation Towards structure-based drug design: crystal structure of a multisubstrate adduct complex of glycinamide ribonucleotide transformylase at 1.96 A resolution.
J.MOL.BIOL.search vol:249, pag:153-175 (1995) [PubMed ID 7776369 ]search
Keywords TRANSFERASE (FORMYL)search
EC 2.1.2.2 ExPASy BRENDA search (A B)
Organism Escherichia coli 562search(A B)
UniProt Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART) P08179search (A B)
Solvent A, B
Polymers
Id Name Type UniProt Residues Observed
A, B GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE Protein P08179 (PUR3_ECOLI)search
 212 96%
Heterogens
Id Name Ligands
A, B N-[4-[[3-(2,4-DIAMINO-1,6-DIHYDRO-6-OXO-4-PYRIMIDINYL)-PROPYL]-[2-((2-OXO-2-((4-PHOSPHORIBOXY)-BUTYL)-AMINO)-ETHYL)-THIO-ACETYL]-AMINO]BENZOYL]-1-GLUTAMIC ACID U89 search
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