Function and Biology

GLUCOAMYLASE-471 COMPLEXED WITH ACARBOSE

Source organism: Aspergillus awamori
Biochemical function: glucan 1,4-alpha-glucosidase activity
Biological process: polysaccharide metabolic process
Cellular component: not assigned

EC 3.2.1.3: Glucan 1,4-alpha-glucosidase

Reaction catalysed:
Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose
Systematic name:
4-alpha-D-glucan glucohydrolase
Alternative Name(s):
  • 1,4-alpha-D-glucan glucohydrolase
  • Acid maltase
  • Amyloglucosidase
  • Exo-1,4-alpha-glucosidase
  • Gamma-1,4-glucan glucohydrolase
  • Gamma-amylase
  • Glucoamylase
  • Glucose amylase
  • Lysosomal alpha-glucosidase

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00723
Domain description: Glycosyl hydrolases family 15
Occurring in:
  1. Glucoamylase
The deposited structure of PDB entry 1gah contains 1 copy of Pfam domain PF00723 (Glycosyl hydrolases family 15) in Glucoamylase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000165
Domain description: Glucoamylase
Occurring in:
  1. Glucoamylase
IPR046966
Domain description: Glucoamylase, active site
Occurring in:
  1. Glucoamylase
IPR011613
Domain description: GH15-like domain
Occurring in:
  1. Glucoamylase
IPR008928
Domain description: Six-hairpin glycosidase superfamily
Occurring in:
  1. Glucoamylase
IPR012341
Domain description: Six-hairpin glycosidase-like superfamily
Occurring in:
  1. Glucoamylase

Structure domain

CATH CATH domain
1.50.10.10
Class: Mainly Alpha
Architecture: Alpha/alpha barrel
Topology: Glycosyltransferase
Homology: Glycosyltransferase
Occurring in:
  1. Glucoamylase
The deposited structure of PDB entry 1gah contains 1 copy of CATH domain 1.50.10.10 (Glycosyltransferase) in Glucoamylase. Showing 1 copy in chain A.
SCOP SCOP annotation
48209
Class: All alpha proteins
Fold: alpha/alpha toroid
Superfamily: Six-hairpin glycosidases
Occurring in:
  1. Glucoamylase
The deposited structure of PDB entry 1gah contains 1 copy of SCOP domain 48209 (Glucoamylase) in Glucoamylase. Showing 1 copy in chain A.