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1g7n Summary pdbe.org/1g7n
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PDB entry 1g7n

Toward changing specificity: adipocyte lipid binding protein mutant, apo form

The structure was published by Reese, A.J. and Banaszak, L.J., in 2004 in a paper entitled "Specificity determinants for lipids bound to beta-barrel proteins." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.5 Å and deposited in 2000.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of ADIPOCYTE LIPID-BINDING PROTEIN. This molecule has the UniProt identifier P04117 (FABP4_MOUSE)search. The sample contained 131 residues which is 99% of the natural sequence. Out of 131 residues 131 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A ADIPOCYTE LIPID-BINDING PROTEIN P04117 (2-132) (FABP4_MOUSE)search Mus musculussearch 98% 131 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P04117 (2 - 132) ADIPOCYTE LIPID-BINDING PROTEIN Mus musculus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P04117) Fatty acid binding protein-likesearch Lipocalinsearch Lipocalin / cytosolic fatty-acid binding protein familysearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A (P04117) Cytokine productionsearch, Negative regulation of protein kinase activitysearch, Transportsearch, Cholesterol homeostasissearch, Negative regulation of transcription, dna-dependentsearch, Positive regulation of inflammatory responsesearch, White fat cell differentiationsearch, Brown fat cell differentiationsearch, Cellular response to lithium ionsearch Lipid bindingsearch Nucleussearch, Cytoplasmsearch

Chain InterPro annotation
A Cytosolic fatty-acid bindingsearch, Lipocalin/cytosolic fatty-acid binding protein domainsearch, Calycin-likesearch, Calycinsearch