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PDBe Entry: 1g4u 
CRYSTAL STRUCTURE OF THE SALMONELLA TYROSINE PHOSPHATASE AND GTPASE ACTIVATING PROTEIN SPTP BOUND TO RAC1
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SIGNALING PROTEIN
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X-RAY DIFFRACTION
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Resolution: 2.3 Å, R-factor: 20.4%, Free R-factor: 25.8%, Spacegroup: P 1
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24/01/2001, deposition: 28/10/2000, last revision: 24/02/2009
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Stebbins, C.E.; Galan, J.E.
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Modulation of host signaling by a bacterial mimic: structure of the Salmonella effector SptP bound to Rac1.
MOL.CELL vol:6, pag:1449-1460 (2000) [PubMed ID 11163217 ]
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virulence factor, GAP, tyrosine phosphatase, 4-helix bundle, GTPase, SIGNALING PROTEIN
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3.1.3.48 ExPASy BRENDA (S)
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Salmonella enterica subsp. enterica serovar Typhimurium 90371(S),Homo sapiens(human) 9606(R)
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Effector protein sptP [Includes: GTPase-activating protein (GAP); Tyrosine-protein phosphatase (EC 3.1.3.48)] P74873 (S)
Ras-related C3 botulinum toxin substrate 1 precursor (p21-Rac1) (Ras-like protein TC25) (Cell migration-inducing gene 5 protein) P63000 (R)
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R, S
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1g4w
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| S |
PROTEIN TYROSINE PHOSPHATASE SPTP |
Protein |
P74873 (SPTP_SALTY)
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383 |
93% |
| R |
RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1 |
Protein |
P63000 (RAC1_HUMAN)
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184 |
97% |
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| R |
MAGNESIUM ION |
MG
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| R |
GUANOSINE-5'-DIPHOSPHATE |
GDP
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| R |
ALUMINUM FLUORIDE |
AF3
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