1g4p Summary



The structure was published by Peapus, D.H., Chiu, H.J., Campobasso, N., Reddick, J.J., Begley, T.P., and Ealick, S.E., in 2001 in a paper entitled "Structural characterization of the enzyme-substrate, enzyme-intermediate, and enzyme-product complexes of thiamin phosphate synthase." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 2000.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of THIAMIN PHOSPHATE SYNTHASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A THIAMIN PHOSPHATE SYNTHASE P39594 (1-222) (THIE_BACSU)search Bacillus subtilis subsp. subtilis str. 168search 100% 226 96%
B THIAMIN PHOSPHATE SYNTHASE P39594 (1-222) (THIE_BACSU)search Bacillus subtilis subsp. subtilis str. 168search 100% 226 96%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P39594 (1 - 222) THIAMIN PHOSPHATE SYNTHASE Bacillus subtilis

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P39594) Thiamin phosphate synthasesearch Aldolase class Isearch PF02581: Thiamine monophosphate synthase/TENIsearch

Chain ID Molecular function (GO) Biological process (GO)
A, B (P39594) catalytic activitysearch thiamine-phosphate diphosphorylase activitysearch transferase activitysearch metal ion bindingsearch magnesium ion bindingsearch thiamine biosynthetic processsearch thiamine diphosphate biosynthetic processsearch

Chain InterPro annotation
A, B Thiamine phosphate synthasesearch Aldolase-type TIM barrelsearch Thiamin phosphate synthase superfamilysearch