1g2t Summary

pdbe.org/1g2t
spacer

SOLUTION STRUCTURE OF EOTAXIN-3

The structure was published by Ye, J., Mayer, K.L., Mayer, M.R., and Stone, M.J., in 2001 in a paper entitled "NMR solution structure and backbone dynamics of the CC chemokine eotaxin-3." (abstract).

The structure was determined using NMR spectroscopy and deposited in 2000.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of EOTAXIN-3. This molecule has the UniProt identifier Q9Y258 (CCL26_HUMAN)search. The sample contained 71 residues which is 100% of the natural sequence. Out of 71 residues 71 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A EOTAXIN-3 Q9Y258 (24-94) (CCL26_HUMAN)search Homo sapienssearch 100% 71 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q9Y258 (24 - 94) EOTAXIN-3 Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (Q9Y258) Interleukin 8-like chemokinessearch OB fold (Dihydrolipoamide Acetyltransferase, E2P)search PF00048: Small cytokines (intecrine/chemokine), interleukin-8 likesearch

Chain ID Cellular component (GO) Biological process (GO) Molecular function (GO)
A (Q9Y258) extracellular regionsearch extracellular spacesearch immune responsesearch positive regulation of cell migrationsearch cell-cell signalingsearch signal transductionsearch cell chemotaxissearch chemotaxissearch inflammatory responsesearch positive regulation of actin filament polymerizationsearch positive regulation of endothelial cell proliferationsearch positive regulation of Rac GTPase activitysearch chemokine activitysearch cytokine activitysearch

Chain InterPro annotation
A CC chemokine, conserved sitesearch Chemokine interleukin-8-like domainsearch