1g2n Summary

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CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF THE ULTRASPIRACLE PROTEIN USP, THE ORTHOLOG OF RXRS IN INSECTS

The structure was published by Billas, I.M., Moulinier, L., Rochel, N., and Moras, D., in 2001 in a paper entitled "Crystal structure of the ligand-binding domain of the ultraspiracle protein USP, the ortholog of retinoid X receptors in insects." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.65 Å and deposited in 2000.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of ULTRASPIRACLE PROTEIN. This molecule has the UniProt identifier Q7SIF6 (Q7SIF6_HELVI)search. The sample contained 264 residues which is 100% of the natural sequence. Out of 264 residues 242 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A ULTRASPIRACLE PROTEIN Q7SIF6 (1-264) (Q7SIF6_HELVI)search Heliothis virescenssearch 99% 264 93%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q7SIF6 (1 - 264) ULTRASPIRACLE PROTEIN Heliothis virescens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (Q7SIF6) Nuclear receptor ligand-binding domainsearch Retinoid X Receptorsearch PF00104: Ligand-binding domain of nuclear hormone receptorsearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A (Q7SIF6) steroid hormone mediated signaling pathwaysearch regulation of transcription, DNA-templatedsearch transcription, DNA-templatedsearch protein bindingsearch steroid hormone receptor activitysearch sequence-specific DNA binding transcription factor activitysearch DNA bindingsearch zinc ion bindingsearch nucleussearch

Chain InterPro annotation
A Retinoid X receptor/HNF4search Nuclear hormone receptor, ligand-binding, coresearch Steroid hormone receptorsearch Nuclear hormone receptor, ligand-bindingsearch